Endocrine Abstracts

Smoking is a modifyable risk factor in the incidence of impaired glucose tolerance and type 2 diabetes, but the data concerning the effect of smoking on the course of type 2 diabetes is limited. In this study, we aimed to investigate a possible relationship between smoking and the need of insulin therapy in patients with type 2 diabetes. 470 patients with type 2 diabetes were assessed for smoking habitus, marital and educational status, duration of diabetes, duration of insuli...

Introduction: Diabetes mellitus (DM) is a common chronic metabolic disease associated with serious complications. Diabetic retinopathy (DR) is one of the most common microvascular complications of DM. The aim of this study was to investigate the association between DR and dyslipidemiaMethods: A total of 1363 subjects were included in this retrospective study. The participants were divided into three groups, including a study group of 352 patients with di...

Inflammation has been shown in obese patients in previous studies. Sick euthyroid syndrome is an expected condition in case of inflammatory diseases. In this study, we aimed to investigate the frequency of sick euthyroid syndrome in obese patients without comorbidities and evaluate the association between obesity and inflammation. A total of 390 subjects were enrolled in this case-control study. The study group consisted of 200 obese patients without comorbidities and the cont...

Introduction: Hepatosteatosis is one of the results of insulin resistance. Thyroid dysfunctions effect on insulin sensitivity. The aim of this study was to evaluate insulin resistance in patients with hepatosteatosis and either hypothyroidism or hyperthyroidism.Design: A total of 407 patients with hepatosteatosis were included. These patients were further divided into two study subgroups and a control group: 102 subjects with hypothyroidism, 103 with hyp...

Introduction: Insulin resistance, refers to decreased response of tissues to insulin, primarily associated with type 2 diabetes and glucose intolerance. Several results were obtained in previous studies about the relation between insulin resistance and thyroid dysfunction. In these studies hepatosteatosis was not an exclusion criteria despite insulin resistance has a key role in the development of it. In this study we aimed to investigate insulin resistance in patients with hy...

Acromegaly is known to be associated with insulin resistance. Visceral adipose tissue is increased in patients with insulin resistance and we aimed to investigate a visceral adipose tissue content as a possible marker of insulin resistance in diabetic and nondiabetic acromegalic patients. We compared 16 diabetic and 16 nondiabetic acromegalic patients for fasting blood glucose (FBG), insulin and visceral adipose tissue content calculated from abdominal computer tomography. All...

Acromegaly is known to be associated with both increased cardiovascular mortality and carbohydrate intolerance. The aim of our study is to compare intima-media thickness, a marker of atherosclerosis in active acromegalic patients with and without diabetes. 32 active acromegalic patients (M/ F: 15/17, 16 diabetic and 16 nondiabetic) were assessed for fasting blood glucose (FBG), insulin, growth hormone, insulin-like growth factor 1 and carotid intima-media thickness (IMT). Diab...

Increased heel pad thickness can be used as a marker of soft tissue enlargement in acromegalic patients. We aimed to investigate if concomittant hyperinsulinemia/and or diabetes secondary to insulin resistance in acromegaly contribute to the enlargement of heel pad. We compared heel pad thickness in 16 diabetic and 16 nondiabetic active acromegalic patients using X-ray images. All of the diabetics were well controlled with diet and/ or oral antidiabetic drugs. GH and IGF-1 wer...

Aim: Subclinical Hypothyroidism (SH) is associated with cardiovascular disorders which may include increased risk for atherosclerosis, endothelial dysfunction and myocardial dysfunction.To investigate the prevalence of left ventricular systolic and diastolic dysfunction in patients with subclinical hypothyroidism and the effect of L-thyroxin therapy on myocardial performance using conventional echocardiographic parameters.Method: The study includes 95 pa...

Background: Diabetes Mellitus (DM) is a disease that increasing in prevalence rapidly in our country and in the world with the increase of sedentary life and unhealthy nutrition. The risks of surgery applied in diabetic patients differ according to other patients.Aim: We aimed to investigate the relationship between the preoperative HbA1c levels and the complications and mortality rates in the postoperative period in patients with diabetes diagnosis and ...